Rs242941
From SNPedia
| Orientation | minus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs242941 |
| PheGenI | rs242941 |
| nextbio | rs242941 |
| hapmap | rs242941 |
| 1000 genomes | rs242941 |
| hgdp | rs242941 |
| ensembl | rs242941 |
| gopubmed | rs242941 |
| geneview | rs242941 |
| scholar | rs242941 |
| rs242941 | |
| pharmgkb | rs242941 |
| gwascentral | rs242941 |
| openSNP | rs242941 |
| 23andMe | rs242941 |
| 23andMe all | rs242941 |
| SNP Nexus | |
| SNPshot | rs242941 |
| SNPdbe | rs242941 |
| MSV3d | rs242941 |
| Gene | CRHR1 |
| Chromosome | 17 |
| Orientation | minus |
| GMAF | 0.3127 |
| Position | 43892520 |
| Reference | GRCh37 37.1/131 |
| Max Magnitude | 0 |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 | better response to inhaled corticosteroid in patients with COPD |
| (G;T) | normal | |
| (T;T) | normal |
rs242941 is a SNP in the corticotrophin-releasing hormone receptor 1 CRHR1 gene.
[PMID 19210659] (G;G) better response to inhaled corticosteroids fluticasone propionate and salmeterol in patients with COPD in a Korean study with 84 subjects.
[PMID 15365580] Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans.
[PMID 19077707] Pharmacogenetics of asthma.
[PMID 19663668] Predictors of poor response during asthma therapy differ with definition of outcome.
[PMID 19750552] Risk and resilience: genetic and environmental influences on development of the stress response.
[PMID 21172166] Pharmacogenetics of antidepressant response.
| GET Evidence | |
|---|---|
| rs242941 | |
| aa_change | |
| aa_change_short | |
| impact | pharmacogenetic |
| qualified_impact | Insufficiently evaluated pharmacogenetic |
| overall_frequency | 0.380952 |
| summary | |
