From SNPedia
rs2304256 is a SNP in the
TYK2 gene on chromosome 19. The most common allele,
rs2304256(C), has been associated with increased risk for systemic
lupus erythematosus (
SLE), with an odds ratio of 1.6 (CI: 1.3-1.9).[
PMID 15657875]
[PMID 19440814] No association was seen between this SNP and SLE in a study of 411 Japanese SLE patients.
| ? | (A;A) (A;C) (C;C) |
|---|
 |
[PMID 19653082] Strong Evidence of a Combination Polymorphism of the Tyrosine Kinase 2 Gene and the Signal Transducer and Activator of Transcription 3 Gene as a DNA-Based Biomarker for Susceptibility to Crohn's Disease in the Japanese Population
[PMID 19714582] Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors
| GWAS snp
|
| PMID
| [PMID 19966805]
|
| Trait
| Type 1 diabetes
|
| Title
| The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes
|
| Risk Allele
| C
|
| P-val
| 4E-9
|
| Odds Ratio
| 1.16 [1.11-1.22]
|
