Rs2290602
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs2290602 |
| hapmap | rs2290602 |
| hgdp | rs2290602 |
| ensembl | rs2290602 |
| gopubmed | rs2290602 |
| scholar | rs2290602 |
| rs2290602 | |
| pharmgkb | rs2290602 |
| hgvbaseg2p | rs2290602 |
| medrefsnp | rs2290602 |
| 23andMe | rs2290602 |
| SNP Nexus |
| Gene | PPARGC1A |
| Chromosome | 4 |
| Orientation | plus |
| Position | 23434829 |
| Genotype | Effect |
|---|---|
| rs2290602(G;G) | normal |
| rs2290602(G;T) | 2.7x increased risk for nonalcoholic fatty liver disease |
| rs2290602(T;T) | 2.7x increased risk for nonalcoholic fatty liver disease |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs2290602(G;G) | normal | |
| Rs2290602(G;T) | 22 | 2.7x increased risk for nonalcoholic fatty liver disease |
| Rs2290602(T;T) | 2.7x increased risk for nonalcoholic fatty liver disease |
rs2290602 is a SNP in the PPARGC1A gene that has been associated with nonalcoholic fatty liver disease (NAFLD). A study of 200 Japanese adults indicated an odds ratio of 2.73 (CI: 1.48-5.06, corrected p = 0.014) for the rs2290602(T) allele.[1]
