rs2279345
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (T;T) | 0 | common in clinvar |
| Make rs2279345(C;C) |
| Make rs2279345(C;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 19 |
| Position | 41009797 |
| Gene | CYP2B6 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2279345 |
| dbSNP (classic) | rs2279345 |
| ClinGen | rs2279345 |
| ebi | rs2279345 |
| HLI | rs2279345 |
| Exac | rs2279345 |
| Gnomad | rs2279345 |
| Varsome | rs2279345 |
| LitVar | rs2279345 |
| Map | rs2279345 |
| PheGenI | rs2279345 |
| Biobank | rs2279345 |
| 1000 genomes | rs2279345 |
| hgdp | rs2279345 |
| ensembl | rs2279345 |
| geneview | rs2279345 |
| scholar | rs2279345 |
| rs2279345 | |
| pharmgkb | rs2279345 |
| gwascentral | rs2279345 |
| openSNP | rs2279345 |
| 23andMe | rs2279345 |
| SNPshot | rs2279345 |
| SNPdbe | rs2279345 |
| MSV3d | rs2279345 |
| GWAS Ctlg | rs2279345 |
| GMAF | 0.2998 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 20639527
] Haplotype structure of CYP2B6 and association with plasma efavirenz concentrations in a Chilean HIV cohort
[PMID 21694616] CYP2B6 polymorphisms influence the plasma concentration and clearance of the methadone S-enantiomer.
| ClinVar | |
|---|---|
| Risk | rs2279345(A;A) rs2279345(C;C) |
| Alt | rs2279345(A;A) rs2279345(C;C) |
| Reference | Rs2279345(T;T) |
| Significance | Drug-response |
| Disease | efavirenz response - Metabolism/PK |
| Variation | info |
| Gene | CYP2B6 |
| CLNDBN | efavirenz response - Metabolism/PK |
| Reversed | 0 |
| HGVS | NC_000019.9:g.41515702T>C |
| CLNSRC | PharmGKB Clinical Annotation PharmGKB |
| CLNACC | RCV000417127.1, |
