Rs2144300

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Orientationplus
Make rs2144300(C;C)
Make rs2144300(C;T)
Make rs2144300(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position230159169
GeneGALNT2
is asnp
is mentioned by
dbSNPrs2144300
Exacrs2144300
PheGenIrs2144300
nextbiors2144300
hapmaprs2144300
1000 genomesrs2144300
hgdprs2144300
ensemblrs2144300
gopubmedrs2144300
geneviewrs2144300
scholarrs2144300
googlers2144300
pharmgkbrs2144300
gwascentralrs2144300
openSNPrs2144300
23andMers2144300
23andMe allrs2144300
SNP Nexus

SNPshotrs2144300
SNPdbers2144300
MSV3drs2144300
GMAF0.3558
? (C;C) (C;T) (T;T) 28
GWAS
SNP rs2144300
PubMedID [PMID 18193043]
Condition HDL cholesterol
Gene GALNT2
Risk Allele T
pValue 3.00E-014
OR 1.11
95% CI NR) mg/dl highe


Neighborrs4846914
Distance775
[PMID 21933382OA-icon.png] Association of the GALNT2 gene polymorphisms and several environmental factors with serum lipid levels in the Mulao and Han populations


[PMID 18852197OA-icon.png] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.


[PMID 19041386OA-icon.png] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.


[PMID 19060911OA-icon.png] Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.


[PMID 19185284OA-icon.png] Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.


[PMID 19435741OA-icon.png] Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.


[PMID 19822575OA-icon.png] Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing.


[PMID 21347282OA-icon.png] Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.


GET Evidence
rs2144300
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.296875
summary



GWAS snp
PMID [PMID 23620142OA-icon.png]
Trait Circulating myeloperoxidase levels (serum)
Title Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia.
Risk Allele C
P-val 3E-6
Odds Ratio .05 [0.030-0.070] unit decrease


[PMID 23832694] Common genetic variants associated with lipid profiles in a Chinese pediatric population.


[PMID 24116192OA-icon.png] Atenolol induced HDL-C change in the pharmacogenomic evaluation of antihypertensive responses (PEAR) study