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rs2075650(A;G)

From SNPedia
possibly 2x higher Alzheimer's risk
Is agenotype
ofrs2075650
GeneTOMM40
Chromosome19
Position44,892,362
mentionedby
Magnitude2
ReputeBad
Geno Mag Summary
(A;A) 0 normal; some association with greater longevity
(A;G) 2 possibly 2x higher Alzheimer's risk
(G;G) 2 possibly 4x higher Alzheimer's risk

Recent work suggests, however, that the linkage disequilibrium between rs2075650 and the ApoE ε4 defining SNP rs429358 means that there may be little, if any, independent effect of rs2075650 on Alzheimer's risk.