rs1805134

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(T;T)	0	common in clinvar

Make rs1805134(C;C)

Make rs1805134(C;T)

Reference

GRCh38 38.1/141

Chromosome

1

Position

65601426

Gene

LEPR

is a	snp
is	mentioned by
dbSNP	rs1805134
dbSNP (classic)	rs1805134
ClinGen	rs1805134
ebi	rs1805134
HLI	rs1805134
Exac	rs1805134
Gnomad	rs1805134
Varsome	rs1805134
LitVar	rs1805134
Map	rs1805134
PheGenI	rs1805134
Biobank	rs1805134
1000 genomes	rs1805134
hgdp	rs1805134
ensembl	rs1805134
geneview	rs1805134
scholar	rs1805134
google	rs1805134
pharmgkb	rs1805134
gwascentral	rs1805134
openSNP	rs1805134
23andMe	rs1805134
SNPshot	rs1805134
SNPdbe	rs1805134
MSV3d	rs1805134
GWAS Ctlg	rs1805134

Merged from

Rs3790419

GMAF

0.1919

Max Magnitude

0

?	(C;C) (C;T) (T;T)

[PMID 18212354] Genes in glucose metabolism and association with spina bifida.

[PMID 19077438] Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations.

[PMID 20032477] Leptin receptor polymorphisms interact with polyunsaturated fatty acids to augment risk of insulin resistance and metabolic syndrome in adults.

[PMID 20416077] Identification of type 2 diabetes-associated combination of SNPs using support vector machine.

[PMID 21204206] Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population.

ClinVar
Risk	rs1805134(C;C)
Alt	rs1805134(C;C)
Reference	Rs1805134(T;T)
Significance	Probable-non-pathogenic
Disease	Monogenic Non-Syndromic Obesity Leptin receptor deficiency
Variation	info
Gene	LEPR LEPROT
CLNDBN	Monogenic Non-Syndromic Obesity Leptin receptor deficiency
Reversed	0
HGVS	NC_000001.10:g.66067109T>C
CLNSRC
CLNACC	RCV000288988.1, RCV000346307.1,