From SNPedia
| ? | (C;C) (C;T) (T;T) | 28 |
|---|
 |
, also known as c.538G>A or G180R, is a SNP in the ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC11 gene.
[PMID 16444273] This SNP determines wet vs dry earwax as well as sweat production, it is also associated with lipid secretion. It is commonly (T;T) for asians and (C;C) for europeans and africans.
gnxp indicates this SNP influences risk of breast cancer in Japanese women. This does not hold true in Caucasian women, though.[PMID 21655989]
| OMIM | 607040 |
| Desc | ATP-BINDING CASSETTE, SUBFAMILY C, MEMBER 11; ABCC11 |
| Variant | |
| Related | also |
[PMID 19650936] A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene
[PMID 20937735] The impact of natural selection on an ABCC11 SNP determining earwax type
