Rs17646946

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Orientationplus
is asnp
is mentioned by
dbSNPrs17646946
PheGenIrs17646946
nextbiors17646946
hapmaprs17646946
1000 genomesrs17646946
hgdprs17646946
ensemblrs17646946
gopubmedrs17646946
geneviewrs17646946
scholarrs17646946
googlers17646946
pharmgkbrs17646946
gwascentralrs17646946
openSNPrs17646946
23andMers17646946
23andMe allrs17646946
SNP Nexus

SNPshotrs17646946
SNPdbers17646946
MSV3drs17646946
GeneTCHHL1
Chromosome1
Orientationplus
GMAF0.1368
Position152090291
ReferenceGRCh38 38.1/141
Max Magnitude2.5
Geno Mag Summary
(A;A) 2.5 straighter curl
(G;G) 0
Make rs17646946(A;G)
? (A;A) (A;G) (G;G) 28
rs17646946 is a SNP on chromosome 1 that is apparently part of the trichohyalin-like 1 TCHHL1 gene. Trichohyalin is a protein found in hair follicle roots.

In an interesting example of people-powered research, this SNP and one other were reported to be associated with hair curliness. Source: [PMID 19896111OA-icon.png] hair curl rs17646946 and rs7349332. source genetic future

rs17646946 and hair curl with each A conferring a reduction in curliness of about 0.29 points on a scale from 0 to 5.

See also: rs11803731

GWAS snp
PMID [PMID 20585627OA-icon.png]
Trait Common traits (Other)
Title Web-based, participant-driven studies yield novel genetic associations for common traits
Risk Allele A
P-val 2E-42
Odds Ratio 0.29 [NR] unit decrease