Rs17646946

Orientation

plus

is a	snp
is	mentioned by
dbSNP	rs17646946
PheGenI	rs17646946
nextbio	rs17646946
hapmap	rs17646946
1000 genomes	rs17646946
hgdp	rs17646946
ensembl	rs17646946
gopubmed	rs17646946
geneview	rs17646946
scholar	rs17646946
google	rs17646946
pharmgkb	rs17646946
gwascentral	rs17646946
openSNP	rs17646946
23andMe	rs17646946
23andMe all	rs17646946
SNP Nexus
SNPshot	rs17646946
SNPdbe	rs17646946
MSV3d	rs17646946

Gene

TCHHL1

Chromosome

1

Orientation

plus

GMAF

0.1378

Position

152062767

Reference

GRCh37.p2 37.2/134

Max Magnitude

2.5

Geno	Mag	Summary
(A;A)	2.5	straighter curl
(G;G)	0

Make rs17646946(A;G)

?	(A;A) (A;G) (G;G)	28

rs17646946 is a SNP on chromosome 1 that is apparently part of the trichohyalin-like 1 TCHHL1 gene. Trichohyalin is a protein found in hair follicle roots.

In an interesting example of people-powered research, this SNP and one other were reported to be associated with hair curliness. Source: [PMID 19896111] hair curl rs17646946 and rs7349332. source genetic future

rs17646946 and hair curl with each A conferring a reduction in curliness of about 0.29 points on a scale from 0 to 5.

See also: rs11803731

GWAS snp
PMID	[PMID 20585627]
Trait	Common traits (Other)
Title	Web-based, participant-driven studies yield novel genetic associations for common traits
Risk Allele	A
P-val	2E-42
Odds Ratio	0.29 [NR] unit decrease