rs17646946 is a SNP on chromosome 1 that is apparently part of the trichohyalin-like 1 TCHHL1 gene. Trichohyalin is a protein found in hair follicle roots.
In an interesting example of people-powered research, this SNP and one other were reported to be associated with hair curliness. Source: [PMID 19896111] hair curl rs17646946 and rs7349332. source genetic future
rs17646946 and hair curl with each A conferring a reduction in curliness of about 0.29 points on a scale from 0 to 5.
See also: rs11803731
|Trait||Common traits (Other)|
|Title||Web-based, participant-driven studies yield novel genetic associations for common traits|
|Odds Ratio||0.29 [NR] unit decrease|