Rs17577
| Orientation | plus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs17577 |
| PheGenI | rs17577 |
| nextbio | rs17577 |
| hapmap | rs17577 |
| 1000 genomes | rs17577 |
| hgdp | rs17577 |
| ensembl | rs17577 |
| gopubmed | rs17577 |
| geneview | rs17577 |
| scholar | rs17577 |
| rs17577 | |
| pharmgkb | rs17577 |
| gwascentral | rs17577 |
| openSNP | rs17577 |
| 23andMe | rs17577 |
| 23andMe all | rs17577 |
| SNP Nexus | |
| SNPshot | rs17577 |
| SNPdbe | rs17577 |
| MSV3d | rs17577 |
| Gene | MMP9, TRIM78P |
| Merged from | Rs2274756 |
| Chromosome | 20 |
| Orientation | plus |
| GMAF | 0.1635 |
| Position | 44643111 |
| Reference | GRCh37.p5 37.3/137 |
| Max Magnitude |
| Make rs17577(A;A) |
| Make rs17577(A;G) |
| Make rs17577(G;G) |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
[PMID 22142952] Personality traits and the R668Q polymorphism located in the MMP-9 gene
[PMID 22621753] Higher risk of matrix metalloproteinase (MMP-2, 7, 9) and tissue inhibitor of metalloproteinase (TIMP-2) genetic variants to gallbladder cancer
[PMID 22664146] Association of matrix metalloproteinases (MMP2, MMP7 and MMP9) genetic variants with left ventricular dysfunction in coronary artery disease patients[PMID 15748780] Genetic association between matrix metalloproteinase MMP-9 and MMP-3 polymorphisms and Japanese sporadic Alzheimer's disease.
[PMID 17346338] Matrix Metalloproteinase-9 (MMP-9) polymorphisms in patients with cutaneous malignant melanoma.
[PMID 18191955] Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools.
[PMID 18303200] Matrix metalloproteinase-3 genotypes influence recovery from hepatitis B virus infection.
[PMID 18636124] Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.
[PMID 19064570] Missense polymorphisms in matrix metalloproteinase genes and skin cancer risk.
[PMID 20078883] Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population.
[PMID 20181264] MMP-9 gene variants increase the risk for non-atopic asthma in children.
[PMID 20184534] Association of matrix metalloproteinase 9 genotypes and cardiovascular disease risk factors with serum matrix metalloproteinase 9 concentrations in Taiwanese individuals.
[PMID 20529372] Matrix metalloproteinase-9 gene polymorphisms in nasal polyposis.
[PMID 20725776] MMP9 polymorphisms and breast cancer risk: a report from the Shanghai Breast Cancer Genetics Study.
[PMID 22107133] Elevated plasma matrix metalloproteinase-9 protein and its gene polymorphism in patients with community-acquired pneumonia.
[PMID 22388798] Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.
| GET Evidence | |
|---|---|
| MMP9-R668Q | |
| aa_change | Arg668Gln |
| aa_change_short | R668Q |
| impact | not reviewed |
| qualified_impact | Insufficiently evaluated not reviewed |
| overall_frequency | 0.134792 |
| summary | |
[PMID 23570558] The Influence of Functional Polymorphisms in Matrix Metalloproteinase 9 on Survival of Breast Cancer Patients in a Chinese Population
[PMID 23639553] Polymorphisms in Metalloproteinase-9 are Associated with the risk for Asthma in Mexican Pediatric Patients
