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Rs16996148

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Orientationplus
is asnp
is mentioned by
dbSNPrs16996148
PheGenIrs16996148
nextbiors16996148
hapmaprs16996148
1000 genomesrs16996148
hgdprs16996148
ensemblrs16996148
gopubmedrs16996148
geneviewrs16996148
scholarrs16996148
googlers16996148
pharmgkbrs16996148
gwascentralrs16996148
openSNPrs16996148
23andMers16996148
23andMe allrs16996148
SNP Nexus

SNPshotrs16996148
SNPdbers16996148
MSV3drs16996148
GeneCILP2
Chromosome19
Orientationplus
GMAF0.101
Position19547663
ReferenceGRCh38 38.1/141
Max Magnitude0
Geno Mag Summary
(G;G) 0 common in complete genomics
Make rs16996148(G;T)
Make rs16996148(T;T)
? (G;G) (G;T) (T;T) 28
GWAS
SNP rs16996148
PubMedID [PMID 18193043]
Condition Triglycerides
Gene NCAN,CILP2
Risk Allele G
pValue 3.00E-009
OR 6.1
95% CI NR) mg/dl highe


GWAS snp
PMID [PMID 18193044OA-icon.png]
Trait LDL cholesterol
Title Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
Risk Allele G
P-val 2.9999999999999997E-8
Odds Ratio 0.10 [0.06-0.14] % SD lower






[PMID 21823004] Effects of SNPs at newly identified lipids loci on blood lipid levels and risk of coronary heart disease in Chinese Han population: A case control study


[PMID 18852197OA-icon.png] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.


[PMID 18987386] Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population.


[PMID 19060910OA-icon.png] Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.


[PMID 19060911OA-icon.png] Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.


[PMID 19197348OA-icon.png] Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.


[PMID 19435741OA-icon.png] Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.


[PMID 19656773OA-icon.png] A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.


[PMID 19951432OA-icon.png] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.


[PMID 21691831] Triglyceride level-influencing functional variants of the ANGPTL3, CILP2, and TRIB1 loci in ischemic stroke.


[PMID 22208664OA-icon.png] Sex-specific association of rs16996148 SNP in the NCAN/CILP2/PBX4 and serum lipid levels in the Mulao and Han populations.


GET Evidence
rs16996148
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.140625
summary



[PMID 23098650] Impact of variants within seven candidate genes on statin treatment efficacy