Rs1537415

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Orientationminus
Geno Mag Summary
(C;C) 0 normal
(C;G) 1.6 1.6x increased risk for periodontitis
(G;G) 2 2x increased risk for periodontitis
ReferenceGRCh38 38.1/141
Chromosome9
Position135637876
GeneGLT6D1
is asnp
is mentioned by
dbSNPrs1537415
PheGenIrs1537415
nextbiors1537415
hapmaprs1537415
1000 genomesrs1537415
hgdprs1537415
ensemblrs1537415
gopubmedrs1537415
geneviewrs1537415
scholarrs1537415
googlers1537415
pharmgkbrs1537415
gwascentralrs1537415
openSNPrs1537415
23andMers1537415
23andMe allrs1537415
SNP Nexus

SNPshotrs1537415
SNPdbers1537415
MSV3drs1537415
GMAF0.3131
Max Magnitude2
? (C;C) (C;G) (G;G) 28
rs1537415 is an intronic SNP in the glycosyltransferase 6 domain containing 1 GLT6D1 gene.

In a combined study of 1,758 Dutch and German subjects, the rs1537415(G) allele was associated with increased risk for periodontitis, at an odds ratio of 1.59 (CI: 1.36-1.86, p=5.5x10e-9).[PMID 19897590]


GET Evidence
rs1537415
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.354839
summary