| Geno
|
Mag
|
Summary
|
| (C;C)
|
0
|
normal
|
| (C;G)
|
1.6
|
1.6x increased risk for periodontitis
|
| (G;G)
|
2
|
2x increased risk for periodontitis
|
| ? | (C;C) (C;G) (G;G) | 28 |
|---|
 |
is an intronic SNP in the glycosyltransferase 6 domain containing 1
GLT6D1 gene.
In a combined study of 1,758 Dutch and German subjects, the rs1537415(G) allele was associated with increased risk for periodontitis, at an odds ratio of 1.59 (CI: 1.36-1.86, p=5.5x10e-9).[PMID 19897590]
| GET Evidence
|
| rs1537415
|
| aa_change
|
|
| aa_change_short
|
|
| impact
|
pathogenic
|
| qualified_impact
|
Insufficiently evaluated pathogenic
|
| overall_frequency
|
0.354839
|
| summary
|
|
