Rs13277113

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is asnp
is mentioned by
dbSNPrs13277113
hapmaprs13277113
hgdprs13277113
ensemblrs13277113
gopubmedrs13277113
scholarrs13277113
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pharmgkbrs13277113
hgvbaseg2prs13277113
medrefsnprs13277113
23andMers13277113
SNP Nexus

Chromosome8
Orientationplus
Position11386595
GenotypeEffect
rs13277113(A;A)*?
rs13277113(A;G)*?
rs13277113(G;G)*?


Associated with systemic lupus erythematosus (SLE) [PMID 18204098]

? (A;A) (A;G) (G;G)
GWAS
SNP rs13277113
PubMedID [PMID 18204098]
Condition Systemic lupus erythematosus
Gene C8orf13, BLK
Risk Allele A
pValue 1.00E-010
OR 1.39
95% CI 1.28-1.51


Related to SYSTEMIC LUPUS ERYTHEMATOSUS, SUSCEPTIBILITY TO, 12; SLEB12 according to omim 612254. See also


Related to TYROSINE KINASE, B-LYMPHOCYTE SPECIFIC; BLK according to omim 191305. See also


Related to FAMILY WITH SEQUENCE SIMILARITY 167, MEMBER A; FAM167A according to omim 610085. See also


[PMID 19714582] Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors

[PMID 19740902] Replication of association between FAM167A(C8orf13)-BLK region and rheumatoid arthritis in a Japanese population

[PMID 19796918] Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations

PharmGKBPA162356732
Name
AnnotationGWAS Results: Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX (Initial Sample Size: 1,311 cases, 3,340 controls; Replication Sample Size: 793 cases, 857 controls; Risk Allele: rs13277113-A).
GeneBLK
Featue
EvidencePubMed ID:18204098; Web Resource:http://www.genome.gov/gwastudies/
Drugs
DiseasesLupus erythematosus, Lupus Erythematosus, Systemic
Curation LevelNon-Curated


[PMID 20131239] Association of FAM167A (C8orf13) - BLK region with systemic sclerosis


[PMID 20156505] Role of the C8orf13-BLK region in biopsy-proven giant cell arteritis