|Condition||Systemic lupus erythematosus|
[PMID 19714582] Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors
[PMID 19740902] Replication of association between FAM167A(C8orf13)-BLK region and rheumatoid arthritis in a Japanese population
[PMID 19796918] Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations
[PMID 20131239] Association of FAM167A (C8orf13) - BLK region with systemic sclerosis
[PMID 20156505] Role of the C8orf13-BLK region in biopsy-proven giant cell arteritis
[PMID 20842512] The association between single-nucleotide polymorphisms of NCF2 and systemic lupus erythematosus in Chinese mainland population
[PMID 22313735] Identify the association between polymorphisms of BLK and systemic lupus erythematosus through unlabelled probe-based high-resolution melting analysis
[PMID 19180478] Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population.
[PMID 19225526] Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese.
[PMID 19442287] Replication of recently identified systemic lupus erythematosus genetic associations: a case-control study.
[PMID 20018015] Elastic-net regularization approaches for genome-wide association studies of rheumatoid arthritis.
[PMID 20018022] Replication of recently identified associated single-nucleotide polymorphisms from six autoimmune diseases in Genetic Analysis Workshop 16 rheumatoid arthritis data.
[PMID 20369022] Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations.
[PMID 21152986] Association of BLK (rs13277113, rs2248932) polymorphism with systemic lupus erythematosus: a meta-analysis.
[PMID 21480188] C8orf13-BLK is a genetic risk locus for systemic sclerosis and has additive effects with BANK1: results from a large french cohort and meta-analysis.
[PMID 21765104] Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: evidence for replication and gene-gene interaction.
|qualified_impact||Insufficiently evaluated pathogenic|
|Trait||Systemic lupus erythematosus|
|Title||Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis.|
|Odds Ratio||1.39 [1.256-1.540]|
[PMID 23646104] Epistatic Interaction between BANK1 and BLK in Rheumatoid Arthritis: Results from a Large Trans-Ethnic Meta-Analysis
[PMID 22696686] Fine mapping and conditional analysis identify a new mutation in the autoimmunity susceptibility gene BLK that leads to reduced half-life of the BLK protein.