Rs1321172

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is asnp
is mentioned by
dbSNPrs1321172
hapmaprs1321172
hgdprs1321172
ensemblrs1321172
gopubmedrs1321172
scholarrs1321172
googlers1321172
pharmgkbrs1321172
hgvbaseg2prs1321172
medrefsnprs1321172
23andMers1321172
SNP Nexus

GenePDE4B
Chromosome1
Orientationminus
Position66503300
GenotypeEffect
rs1321172(G;G)>1.08x risk
rs1321172(C;G)1.08x risk
rs1321172(C;C)common


Genotypes Magnitude Summary
Rs1321172(C;C) common
Rs1321172(C;G) 1.08x risk
Rs1321172(G;G) >1.08x risk

rs1321172 has been reported in a large study to be associated with multiple sclerosis.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with this allele is 1.08 (CI 1.02-1.14). [PMID 17660530]

? (C;C) (C;G) (G;G)
PharmGKBPA162356173
Name
AnnotationIn a replicated GWAS of U.K. and U.S. case/parent trios, this variant was shown to be associated with multiple sclerosis risk.
GenePDE4B
Featue
EvidencePubMed ID:17660530
Drugs
DiseasesMultiple Sclerosis
Curation LevelCurated