Rs12779790
| Orientation | plus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs12779790 |
| PheGenI | rs12779790 |
| nextbio | rs12779790 |
| hapmap | rs12779790 |
| 1000 genomes | rs12779790 |
| hgdp | rs12779790 |
| ensembl | rs12779790 |
| gopubmed | rs12779790 |
| geneview | rs12779790 |
| scholar | rs12779790 |
| rs12779790 | |
| pharmgkb | rs12779790 |
| gwascentral | rs12779790 |
| openSNP | rs12779790 |
| 23andMe | rs12779790 |
| 23andMe all | rs12779790 |
| SNP Nexus | |
| SNPshot | rs12779790 |
| SNPdbe | rs12779790 |
| MSV3d | rs12779790 |
| Chromosome | 10 |
| Orientation | plus |
| GMAF | 0.1726 |
| Position | 12328010 |
| Reference | GRCh37 37.1/131 |
| Max Magnitude |
| Make rs12779790(A;A) |
| Make rs12779790(A;G) |
| Make rs12779790(G;G) |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
| GWAS | |
|---|---|
| SNP | rs12779790 |
| PubMedID | [PMID 18372903] |
| Condition | Type 2 diabetes |
| Gene | CDC123,CAMK1D |
| Risk Allele | G |
| pValue | 1.00E-010 |
| OR | 1.11 |
| 95% CI | 1.07-1.14 |
[PMID 19455301] Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals
[PMID 19789630] Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study
[PMID 18567820] Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
[PMID 18591388] Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk.
[PMID 18694974] Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study.
[PMID 18714373] Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.
[PMID 18782870] Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008.
[PMID 18852197] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
[PMID 19020323] Genotype score in addition to common risk factors for prediction of type 2 diabetes.
[PMID 19056611] Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.
[PMID 19096518] Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.
[PMID 19207020] Meta-analysis in genome-wide association studies.
[PMID 19247373] Testing the association of novel meta-analysis-derived diabetes risk genes with type II diabetes and related metabolic traits in Asian Indian Sikhs.
[PMID 19324937] Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults.
[PMID 19341491] Genome-based prediction of common diseases: methodological considerations for future research.
[PMID 19401414] Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.
[PMID 19460916] Genetic architecture of type 2 diabetes: recent progress and clinical implications.
[PMID 19502414] Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.
[PMID 19526209] Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?
[PMID 19602701] Underlying genetic models of inheritance in established type 2 diabetes associations.
[PMID 19639606] Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.
[PMID 19741467] Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea.
[PMID 19862325] PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population.
[PMID 19956539] How many genetic variants remain to be discovered?
[PMID 20017978] Influence of control selection in genome-wide association studies: the example of diabetes in the Framingham Heart Study.
[PMID 20018041] The effect of multiple genetic variants in predicting the risk of type 2 diabetes.
[PMID 20043853] Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus.
[PMID 20075150] Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study.
[PMID 20144327] A genomics study of type 2 diabetes mellitus in U.S. Air Force personnel.
[PMID 20161779] Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort.
[PMID 20712903] Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.
[PMID 21278902] Genetic risk profiling for prediction of type 2 diabetes.
| GET Evidence | |
|---|---|
| rs12779790 | |
| aa_change | |
| aa_change_short | |
| impact | pathogenic |
| qualified_impact | Insufficiently evaluated pathogenic |
| overall_frequency | 0.117188 |
| summary | |
