Rs12413409

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Orientationplus
Geno Mag Summary
(G;G) 0
Make rs12413409(A;A)
Make rs12413409(A;G)
ReferenceGRCh37 37.1/131
Chromosome10
Position104719096
GeneCNNM2
is asnp
is mentioned by
dbSNPrs12413409
PheGenIrs12413409
nextbiors12413409
hapmaprs12413409
1000 genomesrs12413409
hgdprs12413409
ensemblrs12413409
gopubmedrs12413409
geneviewrs12413409
scholarrs12413409
googlers12413409
pharmgkbrs12413409
gwascentralrs12413409
openSNPrs12413409
23andMers12413409
23andMe allrs12413409
SNP Nexus

SNPshotrs12413409
SNPdbers12413409
MSV3drs12413409
GMAF0.1382
Max Magnitude0
? (A;A) (A;G) (G;G) 28

Based on a large study (~6,000 cases and 14,000 controls) of both European and Japanese populations, the rs12413409(G) allele has been associated with higher risk of aneurysm, with an odds ratio per allele of 1.29 (CI:1.19-1.40, p=1.2e-09). [PMID 20364137OA-icon.png]

Also: 23andMe blog blood pressure

OMIM105800
Desc
Variant
Relatedalso
GWAS snp
PMID [PMID 21378990OA-icon.png]
Trait
Title Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
Risk Allele G
P-val 1E-9
Odds Ratio 1.1200 [1.08-1.16]
GWAS snp
PMID [PMID 21378988]
Trait
Title A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
Risk Allele
P-val 0.000004
Odds Ratio None None

Coronary Heart Disease

High Blood Pressure (Hypertension)

GWAS snp
PMID [PMID 24262325]
Trait Coronary artery disease
Title Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
Risk Allele A
P-val 1E-6
Odds Ratio 1.12 [1.08-1.19]