Rs12413409

Orientation

plus

is a	snp
is	mentioned by
dbSNP	rs12413409
PheGenI	rs12413409
nextbio	rs12413409
hapmap	rs12413409
1000 genomes	rs12413409
hgdp	rs12413409
ensembl	rs12413409
gopubmed	rs12413409
geneview	rs12413409
scholar	rs12413409
google	rs12413409
pharmgkb	rs12413409
gwascentral	rs12413409
openSNP	rs12413409
23andMe	rs12413409
23andMe all	rs12413409
SNP Nexus
SNPshot	rs12413409
SNPdbe	rs12413409
MSV3d	rs12413409

Gene

CNNM2

Chromosome

10

Orientation

plus

GMAF

0.1383

Position

104719096

Reference

GRCh37 37.1/131

Max Magnitude

0

Geno	Mag	Summary
(G;G)	0

Make rs12413409(A;A)

Make rs12413409(A;G)

?	(A;A) (A;G) (G;G)	28

Based on a large study (~6,000 cases and 14,000 controls) of both European and Japanese populations, the rs12413409(G) allele has been associated with higher risk of aneurysm, with an odds ratio per allele of 1.29 (CI:1.19-1.40, p=1.2e-09). [PMID 20364137]

Also: 23andMe blog blood pressure

OMIM	105800
Desc
Variant
Related	also

GWAS snp
PMID	[PMID 21378990]
Trait
Title	Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
Risk Allele	G
P-val	1E-9
Odds Ratio	1.1200 [1.08-1.16]

GWAS snp
PMID	[PMID 21378988]
Trait
Title	A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
Risk Allele
P-val	0.000004
Odds Ratio	None None

Coronary Heart Disease

High Blood Pressure (Hypertension)