rs11676382
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in clinvar |
| Make rs11676382(C;G) |
| Make rs11676382(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 2 |
| Position | 85550510 |
| Gene | GGCX |
| is a | snp |
| is | mentioned by |
| dbSNP | rs11676382 |
| dbSNP (classic) | rs11676382 |
| ClinGen | rs11676382 |
| ebi | rs11676382 |
| HLI | rs11676382 |
| Exac | rs11676382 |
| Gnomad | rs11676382 |
| Varsome | rs11676382 |
| LitVar | rs11676382 |
| Map | rs11676382 |
| PheGenI | rs11676382 |
| Biobank | rs11676382 |
| 1000 genomes | rs11676382 |
| hgdp | rs11676382 |
| ensembl | rs11676382 |
| geneview | rs11676382 |
| scholar | rs11676382 |
| rs11676382 | |
| pharmgkb | rs11676382 |
| gwascentral | rs11676382 |
| openSNP | rs11676382 |
| 23andMe | rs11676382 |
| SNPshot | rs11676382 |
| SNPdbe | rs11676382 |
| MSV3d | rs11676382 |
| GWAS Ctlg | rs11676382 |
| GMAF | 0.03719 |
| Max Magnitude | 0 |
| ? | (C;C) (C;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 17764537] rs11676382 was associated with a warfarin maintenance dose across all analysis methods. the effects of GGCX are potentially population/treatment-dependent and will not have broad utility for determining warfarin dosing.
[PMID 20694283
] Gamma-glutamyl carboxylase and its influence on warfarin dose
[PMID 25681132] Impact of gamma-glutamyl carboxylase gene polymorphisms on warfarin dose requirement: A systematic review and meta-analysis
| ClinVar | |
|---|---|
| Risk | rs11676382(G;G) |
| Alt | rs11676382(G;G) |
| Reference | Rs11676382(C;C) |
| Significance | Drug-response |
| Disease | warfarin response - Dosage |
| Variation | info |
| Gene | GGCX |
| CLNDBN | warfarin response - Dosage |
| Reversed | 0 |
| HGVS | NC_000002.11:g.85777633C>G |
| CLNSRC | |
| CLNACC | RCV000417158.1, |
