From SNPedia
A large study of Caucasian children has identified this SNP in the
TBX21 gene (and one other,
rs16947078) as defining a haplotype associated with increased risk for allergic
asthma. [
PMID 17949803]
The odds ratio associated with rs11650354(T;T) homozygotes compared to rs11650354(C;C) homozygotes for allergic asthma is reported to be 8.13 (CI: 2.5-26.9). Heterozygotes may be at slightly higher risk. [PMID 17949803]
| ? | (C;C) (C;T) (T;T) |
|---|
 |
[PMID 19950257] Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: Evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines
