Rs11594656
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs11594656 |
| hapmap | rs11594656 |
| hgdp | rs11594656 |
| ensembl | rs11594656 |
| gopubmed | rs11594656 |
| scholar | rs11594656 |
| rs11594656 | |
| pharmgkb | rs11594656 |
| hgvbaseg2p | rs11594656 |
| medrefsnp | rs11594656 |
| 23andMe | rs11594656 |
| SNP Nexus |
| Chromosome | 10 |
| Orientation | plus |
| Position | 6162014 |
| Genotype | Effect |
|---|---|
| rs11594656(A;A)* | ? |
| rs11594656(A;T)* | ? |
| rs11594656(T;T)* | ? |
| Rs11594656 | |
|---|---|
| PubMed | [PMID 17676041] |
| Affy Probeset | SNP_A-8400635 |
| Affy Orientation | reverse |
| On GW 5.0 | 0 |
| Alleles A/B | A/T |
| Ancestral | T |
| Population | CEU |
| Allele | T |
| Case Freq. | 0.78 |
| Control Freq. | 0.75 |
| Odds Ratio Het | 1.19 |
| Odds Ratio Hom | 1.38 |
| Odds Ratio All | 1.22 |
| Disease | Type I Diabetes (T1D) |
| ? | (A;A) (A;T) (T;T) |
|---|---|
|
| |
rs11594656 increases susceptibility to Type I Diabetes 1.19 times for heterozygotes (AT) and 1.38 times for homozygotes (TT) [PMID 17676041]
[PMID 19265545] Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.
Related to INTERLEUKIN 2 RECEPTOR, ALPHA; IL2RA
according to omim 147730. See also
[PMID 19956099] The type I diabetes association of the IL2RA locus
[PMID 20033399] Single-nucleotide polymorphisms in the IL2RA gene are associated with age at diagnosis in late-onset Finnish type 1 diabetes subjects
