Rs11574637
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs11574637 |
| hapmap | rs11574637 |
| hgdp | rs11574637 |
| ensembl | rs11574637 |
| gopubmed | rs11574637 |
| scholar | rs11574637 |
| rs11574637 | |
| pharmgkb | rs11574637 |
| hgvbaseg2p | rs11574637 |
| medrefsnp | rs11574637 |
| 23andMe | rs11574637 |
| SNP Nexus |
| Gene | ITGAX |
| Orientation | plus |
| Position | 31276374 |
| Genotype | Effect |
|---|---|
| rs11574637(C;C)* | ? |
| rs11574637(C;T)* | ? |
| rs11574637(T;T)* | ? |
Associated with systemic lupus erythematosus (SLE) [PMID 18204098]
| ? | (C;C) (C;T) (T;T) |
|---|---|
|
| |
| GWAS | |
|---|---|
| SNP | rs11574637 |
| PubMedID | [PMID 18204098] |
| Condition | Systemic lupus erythematosus |
| Gene | ITGAM, ITGAX |
| Risk Allele | C |
| pValue | 3.00E-011 |
| OR | 1.33 |
| 95% CI | 1.22-1.46 |
Related to SYSTEMIC LUPUS ERYTHEMATOSUS, SUSCEPTIBILITY TO, 6; SLEB6
according to omim 609939. See also
Related to INTEGRIN, ALPHA-X; ITGAX
according to omim 151510. See also
| PharmGKB | PA162356731 |
| Name | |
| Annotation | GWAS Results: Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX (Initial Sample Size: 1,311 cases, 3,340 controls; Replication Sample Size: 793 cases, 857 controls; Risk Allele: rs11574637-C). |
| Gene | ITGAX |
| Featue | |
| Evidence | PubMed ID:18204098; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Lupus erythematosus, Lupus Erythematosus, Systemic |
| Curation Level | Non-Curated |
