Rs1143674

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is asnp
is mentioned by
dbSNPrs1143674
hapmaprs1143674
hgdprs1143674
ensemblrs1143674
gopubmedrs1143674
scholarrs1143674
googlers1143674
pharmgkbrs1143674
hgvbaseg2prs1143674
medrefsnprs1143674
23andMers1143674
SNP Nexus

GeneITGA4
Chromosome2
Orientationplus
Position182082778
GenotypeEffect
rs1143674(A;A)1.3x increased autism risk
rs1143674(A;G)1.3x increased autism risk
rs1143674(G;G)normal


Genotypes Magnitude Summary
Rs1143674(A;A) 1.3x increased autism risk
Rs1143674(A;G) 1.3x increased autism risk
Rs1143674(G;G) normal

rs1143674 is a SNP in the integrin alpha-4 ITGA4 gene on chromosome 2.

Across two sets of family samples (Irish and American), rs1143674 showed a slight association with increased risk for autism, with an odds ratio of 1.3 (p = 0.008). [PMID 18846500]