[PMID 21638280] 2'-5' oligoadenylate synthetase 1 polymorphism is associated with prostate cancer
|CLNDBN||Diabetes mellitus, type 1, susceptibility to|
|CLNSRC||OMIM Allelic Variant|
[PMID 15732009] Variation in antiviral 2',5'-oligoadenylate synthetase (2'5'AS) enzyme activity is controlled by a single-nucleotide polymorphism at a splice-acceptor site in the OAS1 gene.
[PMID 19247438] Genetic variation in OAS1 is a risk factor for initial infection with West Nile virus in man.
[PMID 19434718] Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.
[PMID 19956101] Overview of the Rapid Response data.
[PMID 19956105] Reassessment of the type I diabetes association of the OAS1 locus.
[PMID 20079393] 2'-5'-Oligoadenylate synthetase single-nucleotide polymorphisms and haplotypes are associated with variations in immune responses to rubella vaccine.
|qualified_impact||Insufficiently evaluated not reviewed|
[PMID 22710942] Evaluate the relationship between polymorphisms of OAS1 gene and susceptibility to chronic hepatitis C with high resolution melting analysis.
[PMID 23337612] Polymorphisms in the oligoadenylate synthetase gene cluster and its association with clinical outcomes of dengue virus infection.
[PMID 25205466] Mitochondrial localization of the OAS1 p46 isoform associated with a common single nucleotide polymorphism