Rs1128535

From SNPedia

The less common allele of rs1128535, a SNP in the TRAIP gene, may have a protective effect against the development of Crohn's disease, based on a study of 469 Caucasian patients. The reported odds ratio is 0.77 (CI: 0.67-0.89, p=0.002).[PMID 18200509]

Note that rs1128535 is highly correlated (r² > 0.8) to nonsynonymous SNPs in the nearby MST1R gene, rs2230590 and rs1062633, also known as Arg523Gln and Gly1335Arg, respectively. [PMID 18200509]

[PMID 19657358] Effect of BSN-MST1 locus on inflammatory bowel disease and multiple sclerosis susceptibility