|Trait||Systolic blood pressure|
|Title||Genome-wide association study identifies eight loci associated with blood pressure|
|Odds Ratio||1.16 [0.92-1.40] mm Hg increase|
|Title||Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.|
|Odds Ratio||1.1800 [0.91-1.45] mm Hg increase|
[PMID 21963141] Genetic variations in CYP17A1, CACNB2 and PLEKHA7 are associated with blood pressure and/or hypertension in she ethnic minority of China
|Title||Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.|
|Odds Ratio||1.0950 [NR] mmHg increase|
|Title||Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.|
|Odds Ratio||0.5290 [0.37-0.69] mmHg increase|
[PMID 20852445] Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated with blood pressure and hypertension in Chinese Hans.
[PMID 22504314] Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium.
[PMID 22525200] Pharmacogenetic implications for eight common blood pressure-associated single-nucleotide polymorphisms.
|qualified_impact||Insufficiently evaluated pathogenic|
[PMID 23133444] Genetic variation in CYP17A1 is associated with arterial stiffness in diabetic subjects
[PMID 22048715] A sex-specific effect of the CYP17A1 SNP rs11191548 on blood pressure in Chinese children
[PMID 22959498] Recapitulation of four hypertension susceptibility genes (CSK, CYP17A1, MTHFR, and FGF5) in East Asians.
[PMID 23467202] Common polymorphism rs11191548 near the CYP17A1 gene is associated with hypertension and systolic blood pressure in the Han Chinese population.