Rs11191548

From SNPedia
Jump to: navigation, search

Orientationplus
is asnp
is mentioned by
dbSNPrs11191548
PheGenIrs11191548
nextbiors11191548
hapmaprs11191548
1000 genomesrs11191548
hgdprs11191548
ensemblrs11191548
gopubmedrs11191548
geneviewrs11191548
scholarrs11191548
googlers11191548
pharmgkbrs11191548
gwascentralrs11191548
openSNPrs11191548
23andMers11191548
23andMe allrs11191548
SNP Nexus

SNPshotrs11191548
SNPdbers11191548
MSV3drs11191548
GeneNT5C2
Chromosome10
Orientationplus
GMAF0.1345
Position104846178
ReferenceGRCh37 37.1/131
Max Magnitude0
Geno Mag Summary
(T;T) 0
Make rs11191548(C;C)
Make rs11191548(C;T)
? (C;C) (C;T) (T;T) 28
[PMID 19430483OA-icon.png]

23andMe blog blood pressure

GWAS snp
PMID [PMID 19430483OA-icon.png]
Trait Systolic blood pressure
Title Genome-wide association study identifies eight loci associated with blood pressure
Risk Allele T
P-val 7E-24
Odds Ratio 1.16 [0.92-1.40] mm Hg increase
GWAS snp
PMID [PMID 21572416OA-icon.png]
Trait
Title Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.
Risk Allele T
P-val 4E-17
Odds Ratio 1.1800 [0.91-1.45] mm Hg increase


[PMID 21963141] Genetic variations in CYP17A1, CACNB2 and PLEKHA7 are associated with blood pressure and/or hypertension in she ethnic minority of China

GWAS snp
PMID [PMID 21909115OA-icon.png]
Trait
Title Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Risk Allele T
P-val 7E-26
Odds Ratio 1.0950 [NR] mmHg increase
GWAS snp
PMID [PMID 21909110OA-icon.png]
Trait
Title Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
Risk Allele T
P-val 8E-11
Odds Ratio 0.5290 [0.37-0.69] mmHg increase


[PMID 20852445] Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated with blood pressure and hypertension in Chinese Hans.


[PMID 22504314OA-icon.png] Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium.


[PMID 22525200] Pharmacogenetic implications for eight common blood pressure-associated single-nucleotide polymorphisms.


GET Evidence
rs11191548
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.046875
summary



[PMID 23133444OA-icon.png] Genetic variation in CYP17A1 is associated with arterial stiffness in diabetic subjects


[PMID 22048715] A sex-specific effect of the CYP17A1 SNP rs11191548 on blood pressure in Chinese children


[PMID 22959498] Recapitulation of four hypertension susceptibility genes (CSK, CYP17A1, MTHFR, and FGF5) in East Asians.


[PMID 23467202] Common polymorphism rs11191548 near the CYP17A1 gene is associated with hypertension and systolic blood pressure in the Han Chinese population.