| ? | (C;C) (C;T) (T;T) | 28 |
|---|
 |
| Rs11190302
|
| PubMed
|
[PMID 16740596]
|
| Affy Probeset
|
SNP_A-8415319
|
| Affy Orientation
|
reverse
|
| On GW 5.0
|
0
|
| Alleles A/B
|
A/G
|
| Ancestral
|
T
|
| Population
|
Japanese
|
| Allele
|
T
|
| Case Freq.
|
0.26
|
| Control Freq.
|
0.2
|
| Odds Ratio Het
|
1.39
|
| Odds Ratio Hom
|
2.07
|
| Odds Ratio All
|
1.44
|
| Disease
|
Alzheimer's disease, late-onset (LOAD)
|
rs11190302 increases susceptibility to late-onset Alzheimer's disease 1.39 times for heterozygotes (CT) and 2.07 times for homozygotes (TT). [PMID 16740596]
[PMID 18452187] Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample
[PMID 18359537] DNMBP is genetically associated with Alzheimer dementia in the Belgian population.
