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Rs11052552

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Orientationplus
is asnp
is mentioned by
dbSNPrs11052552
PheGenIrs11052552
nextbiors11052552
hapmaprs11052552
1000 genomesrs11052552
hgdprs11052552
ensemblrs11052552
gopubmedrs11052552
geneviewrs11052552
scholarrs11052552
googlers11052552
pharmgkbrs11052552
gwascentralrs11052552
openSNPrs11052552
23andMers11052552
23andMe allrs11052552
SNP Nexus

SNPshotrs11052552
SNPdbers11052552
MSV3drs11052552
GeneCLECL1
Chromosome12
Orientationplus
GMAF0.4596
Position9703362
ReferenceGRCh38 38.1/141
Max Magnitude0
Geno Mag Summary
(G;G) 1.4x risk
(G;T) 1.5x risk
(T;T) 0 normal
? (G;G) (G;T) (T;T) 28
rs11052552 has been reported in a large study to be associated with type-1 diabetes.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.49 (CI 1.28-1.73), and for homozygotes, 1.43 (CI 1.21-1.69). [PMID 17554300OA-icon.png]

GWAS
SNP rs11052552
PubMedID [PMID 17554300OA-icon.png]
Condition Type 1 diabetes
Gene NR
Risk Allele G
pValue 7.00E-007
OR 1.49
95% CI 1.28-1.73



[PMID 22496761OA-icon.png] Improving Power of Genome-Wide Association Studies with Weighted False Discovery Rate Control and Prioritized Subset Analysis


GET Evidence
rs11052552
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.381356
summary