Rs11052552
From SNPedia
| Orientation | plus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs11052552 |
| PheGenI | rs11052552 |
| nextbio | rs11052552 |
| hapmap | rs11052552 |
| 1000 genomes | rs11052552 |
| hgdp | rs11052552 |
| ensembl | rs11052552 |
| gopubmed | rs11052552 |
| geneview | rs11052552 |
| scholar | rs11052552 |
| rs11052552 | |
| pharmgkb | rs11052552 |
| gwascentral | rs11052552 |
| openSNP | rs11052552 |
| 23andMe | rs11052552 |
| 23andMe all | rs11052552 |
| SNP Nexus | |
| SNPshot | rs11052552 |
| SNPdbe | rs11052552 |
| MSV3d | rs11052552 |
| Chromosome | 12 |
| Orientation | plus |
| GMAF | 0.4592 |
| Position | 9855958 |
| Reference | GRCh37 37.1/131 |
| Max Magnitude | 0 |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 1.4x risk | |
| (G;T) | 1.5x risk | |
| (T;T) | 0 | normal |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.49 (CI 1.28-1.73), and for homozygotes, 1.43 (CI 1.21-1.69). [PMID 17554300]
| GWAS | |
|---|---|
| SNP | rs11052552 |
| PubMedID | [PMID 17554300] |
| Condition | Type 1 diabetes |
| Gene | NR |
| Risk Allele | G |
| pValue | 7.00E-007 |
| OR | 1.49 |
| 95% CI | 1.28-1.73 |
[PMID 22496761] Improving Power of Genome-Wide Association Studies with Weighted False Discovery Rate Control and Prioritized Subset Analysis
| GET Evidence | |
|---|---|
| rs11052552 | |
| aa_change | |
| aa_change_short | |
| impact | pathogenic |
| qualified_impact | Insufficiently evaluated pathogenic |
| overall_frequency | 0.381356 |
| summary | |
