| ? | (A;A) (A;G) (G;G) | 28 |
|---|
 |
| GWAS snp
|
| PMID
|
[PMID 20453838]
|
| Trait
|
Breast cancer
|
| Title
|
Genome-wide association study identifies five new breast cancer susceptibility loci
|
| Risk Allele
|
G
|
| P-val
|
5E-15
|
| Odds Ratio
|
1.16 [1.10-1.22]
|
23andMe blog each copy of an A at rs10995190 was associated with a 2% decrease in mammographic density. The researchers also found that each copy of an A at rs10995190 is also associated with slightly lower odds of developing breast cancer
[PMID 21445572] Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies
| GWAS snp
|
| PMID
|
[PMID 21278746]
|
| Trait
|
|
| Title
|
Common variants in ZNF365 are associated with both mammographic density and breast cancer risk
|
| Risk Allele
|
A
|
| P-val
|
1E-9
|
| Odds Ratio
|
0.1800 [0.12-0.25] % decrease
|
[PMID 22348646] Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers
[PMID 22461340] 11q13 is a susceptibility locus for hormone receptor positive breast cancer
Breast Cancer Risk Modifiers
