Rs10984447
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs10984447 |
| hapmap | rs10984447 |
| hgdp | rs10984447 |
| ensembl | rs10984447 |
| gopubmed | rs10984447 |
| scholar | rs10984447 |
| rs10984447 | |
| pharmgkb | rs10984447 |
| hgvbaseg2p | rs10984447 |
| medrefsnp | rs10984447 |
| 23andMe | rs10984447 |
| SNP Nexus |
| Gene | DBC1 |
| Chromosome | 9 |
| Orientation | plus |
| Position | 121024373 |
| Genotype | Effect |
|---|---|
| rs10984447(A;A) | >1.17x risk |
| rs10984447(A;G) | 1.17x risk |
| rs10984447(G;G) | common |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs10984447(A;A) | >1.17x risk | |
| Rs10984447(A;G) | 1.17x risk | |
| Rs10984447(G;G) | common |
rs10984447 has been reported in a large study to be associated with multiple sclerosis.
The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with this allele is 1.17 (CI 1.09-1.25). [PMID 17660530]
| ? | (A;A) (A;G) (G;G) |
|---|---|
|
| |
| GWAS | |
|---|---|
| SNP | rs10984447 |
| PubMedID | [PMID 17660530] |
| Condition | Multiple sclerosis |
| Gene | DBC1 |
| Risk Allele | A |
| pValue | 8.00E-006 |
| OR | 1.17 |
| 95% CI | 1.09-1.25 |
| PharmGKB | PA162356163 |
| Name | |
| Annotation | In a replicated GWAS of U.K. and U.S. case/parent trios, this variant was shown to be associated with multiple sclerosis risk. |
| Gene | DBC1 |
| Featue | |
| Evidence | PubMed ID:17660530 |
| Drugs | |
| Diseases | Multiple Sclerosis |
| Curation Level | Curated |
