Rs10821936
From SNPedia
| Orientation | plus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10821936 |
| PheGenI | rs10821936 |
| nextbio | rs10821936 |
| hapmap | rs10821936 |
| 1000 genomes | rs10821936 |
| hgdp | rs10821936 |
| ensembl | rs10821936 |
| gopubmed | rs10821936 |
| geneview | rs10821936 |
| scholar | rs10821936 |
| rs10821936 | |
| pharmgkb | rs10821936 |
| gwascentral | rs10821936 |
| openSNP | rs10821936 |
| 23andMe | rs10821936 |
| 23andMe all | rs10821936 |
| SNP Nexus | |
| SNPshot | rs10821936 |
| SNPdbe | rs10821936 |
| MSV3d | rs10821936 |
| Gene | ARID5B |
| Chromosome | 10 |
| Orientation | plus |
| GMAF | 0.3109 |
| Position | 63723577 |
| Reference | GRCh37 37.1/131 |
| Max Magnitude |
| Make rs10821936(C;C) |
| Make rs10821936(C;T) |
| Make rs10821936(T;T) |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
| GWAS snp | |
|---|---|
| PMID | [PMID 19684603] |
| Trait | Acute lymphoblastic leukemia (childhood) |
| Title | Germline genomic variants associated with childhood acute lymphoblastic leukemia |
| Risk Allele | C |
| P-val | 1E-15 |
| Odds Ratio | 1.91 [1.60-2.20] |
[PMID 22291082] ARID5B Genetic Polymorphisms Contribute to Racial Disparities in the Incidence and Treatment Outcome of Childhood Acute Lymphoblastic Leukemia
[PMID 22422485] Genetic variants modify susceptibility to leukemia in infants: A Children's Oncology Group report
[PMID 20460642] Replication analysis confirms the association of ARID5B with childhood B-cell acute lymphoblastic leukemia.
| GET Evidence | |
|---|---|
| rs10821936 | |
| aa_change | |
| aa_change_short | |
| impact | pathogenic |
| qualified_impact | Insufficiently evaluated pathogenic |
| overall_frequency | 0.6875 |
| summary | |
[PMID 23608171] Association of three polymorphisms in ARID5B, IKZF1and CEBPE with the risk of childhood acute lymphoblastic leukemia in a Chinese population
