Rs10008492
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs10008492 |
| hapmap | rs10008492 |
| hgdp | rs10008492 |
| ensembl | rs10008492 |
| gopubmed | rs10008492 |
| scholar | rs10008492 |
| rs10008492 | |
| pharmgkb | rs10008492 |
| hgvbaseg2p | rs10008492 |
| medrefsnp | rs10008492 |
| 23andMe | rs10008492 |
| SNP Nexus |
| Chromosome | 4 |
| Orientation | plus |
| Position | 38442114 |
| Genotype | Effect |
|---|---|
| rs10008492(C;C) | normal |
| rs10008492(C;T) | 1.1x increased risk for Non-hodgkin's lymphoma |
| rs10008492(T;T) | 1.4x increased risk for Non-hodgkin's lymphoma |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs10008492(C;C) | normal | |
| Rs10008492(C;T) | 1.1x increased risk for Non-hodgkin's lymphoma | |
| Rs10008492(T;T) | 1.4x increased risk for Non-hodgkin's lymphoma |
In a pooled analysis including three population-based case-control studies of Non-Hodgkin's lymphoma (1,946 cases, 1,808 controls), two SNPs in moderate linkage disequilibrium were significantly associated with NHL: rs10008492 (odds ratio for (C;T) genotype 1.12, CI: 0.97-1.30; OR(T;T) 1.40, CI: 1.15-1.71; p(trend)=0.001) and rs4833103 (OR(A;C) 0.75, CI: 0.64-0.88; OR(A;A) 0.74, CI: 0.62-0.90; p(trend)=0.002; p(dominant)=0.0002).[PMID 19029192]
| ? | (C;C) (C;T) (T;T) |
|---|---|
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