OR7D4
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | olfactory receptor, family 7, subfamily D, member 4 |
| EntrezGene | 125958 |
| PheGenI | 125958 |
| VariationViewer | 125958 |
| ClinVar | OR7D4 |
| GeneCards | OR7D4 |
| dbSNP | 125958 |
| Diseases | OR7D4 |
| SADR | 125958 |
| HugeNav | 125958 |
| wikipedia | OR7D4 |
| OR7D4 | |
| gopubmed | OR7D4 |
| EVS | OR7D4 |
| HEFalMp | OR7D4 |
| MyGene2 | OR7D4 |
| 23andMe | OR7D4 |
| UniProt | Q8NG98 |
| Ensembl | ENSG00000174667 |
| OMIM | 611538 |
| # SNPs | 3 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs2878329 | 0 | 9,215,066 | |
| rs5020278 | 0 | 9,214,440 | |
| rs61729907 | 0 | 9,214,576 |
[PMID 17873857] Genetic variation in a human odorant receptor alters odour perception.
A common variant of the receptor OR7D4, OR7D4 WM contains two non-synonymous single nucleotide polymorphisms (SNPs), resulting in two amino acid substitutions (rs61729907 or R88W, and rs5020278 or T133M; hence 'RT') that severely impair function in vitro. Human subjects with RT/WM or WM/WM genotypes as a group were less sensitive to androstenone and androstadienone and found both odours less unpleasant than the RT/RT group.
