LSAMP

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is agene
is mentioned by
EntrezGene4045
PheGenI4045
VariationViewer4045
ClinVarLSAMP
dbSNP4045
SADR4045
HugeNav4045
wikipediaLSAMP
googleLSAMP
gopubmedLSAMP
EVSLSAMP
HEFalMpLSAMP
23andMeLSAMP
EVSLSAMP
# SNPs2
 Max MagnitudeChromosome positionSummary
Rs1676232117,515,992
Rs4404477117,655,921

LSAMP encodes limbic-system associated membrane protein.

[PMID 18318786] - A 'novel alternative transcript' haplotype within LSAMP associated with left-main coronary artery disease. LSAMP function was determined to be relevant to smooth muscle cell proliferation, as blocking it entirely led to greatly increased smooth muscle cell proliferation in human aortic SMCs. rs1676232(A) and rs4404477(A), among others, appear to denote this haplotype (see AEHA 2008 ppt, or a google search for a more applicable patent)

[PMID 18433483] possible association with suicide, although the SNPs found (rs2918215, rs2918213, rs9874470, rs4821129, all major alleles) to be associated did not survive multiple correction, and no haploblocks exhibited statistical significance.