HMGCR
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | 3-hydroxy-3-methylglutaryl-CoA reductase |
| EntrezGene | 3156 |
| PheGenI | 3156 |
| VariationViewer | 3156 |
| ClinVar | HMGCR |
| GeneCards | HMGCR |
| dbSNP | 3156 |
| Diseases | HMGCR |
| SADR | 3156 |
| HugeNav | 3156 |
| wikipedia | HMGCR |
| HMGCR | |
| gopubmed | HMGCR |
| EVS | HMGCR |
| HEFalMp | HMGCR |
| MyGene2 | HMGCR |
| 23andMe | HMGCR |
| UniProt | P04035 |
| Ensembl | ENSG00000113161 |
| OMIM | 142910 |
| # SNPs | 11 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs10045497 | 0 | 75,340,659 | |
| rs12654264 | 0 | 75,352,778 | |
| rs12916 | 0 | 75,360,714 | |
| rs17238484 | 0 | 75,352,671 | |
| rs17238540 | 0 | 75,359,673 | |
| rs17244841 | 0 | 75,347,030 | |
| rs3761740 | 0 | 75,336,308 | |
| rs3846662 | 0 | 75,355,259 | |
| rs3846663 | 0 | 75,359,901 | |
| rs4629571 | 0 | 75,362,479 | |
| rs5908 | 0 | 75,356,374 |
The HMGCR gene encodes HMG-CoA reductase, a protein best known as being the target for drugs designed to reduce cholesterol levels and thereby reduce the risk for heart disease.
SNPs in HMGCR can influence how well such drugs work; they include:
