rs80359641

plus

Geno	Mag	Summary
(-;CCAA)	6	BRCA2 variant considered pathogenic for breast cancer
(ACCA;ACCA)	0	common in clinvar
(CCAA;CCAA)	0	common in clinvar

Make rs80359641(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32355061

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359641
dbSNP (classic)	rs80359641
ClinGen	rs80359641
ebi	rs80359641
HLI	rs80359641
Exac	rs80359641
Gnomad	rs80359641
Varsome	rs80359641
LitVar	rs80359641
Map	rs80359641
PheGenI	rs80359641
Biobank	rs80359641
1000 genomes	rs80359641
hgdp	rs80359641
ensembl	rs80359641
geneview	rs80359641
scholar	rs80359641
google	rs80359641
pharmgkb	rs80359641
gwascentral	rs80359641
openSNP	rs80359641
23andMe	rs80359641
SNPshot	rs80359641
SNPdbe	rs80359641
MSV3d	rs80359641
GWAS Ctlg	rs80359641

Max Magnitude

6

rs80359641, also known as 7436del4, c.7208_7211delCCAA and p.Thr2403_Lys2404?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359641(-;-) Rs80359641(ACCA;ACCA)
Alt	rs80359641(-;-) Rs80359641(ACCA;ACCA)
Reference	Rs80359641(CCAA;CCAA)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Reversed	0
HGVS	NC_000013.10:g.32929198_32929201delCCAA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000077399.7, RCV000215912.1, RCV000257918.3,