rs80359623

plus

Geno	Mag	Summary
(-;CT)	6	BRCA2 variant considered pathogenic for breast cancer
(CT;CT)	0	common in clinvar
(TC;TC)	0	common in clinvar

Make rs80359623(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32341112

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359623
dbSNP (classic)	rs80359623
ClinGen	rs80359623
ebi	rs80359623
HLI	rs80359623
Exac	rs80359623
Gnomad	rs80359623
Varsome	rs80359623
LitVar	rs80359623
Map	rs80359623
PheGenI	rs80359623
Biobank	rs80359623
1000 genomes	rs80359623
hgdp	rs80359623
ensembl	rs80359623
geneview	rs80359623
scholar	rs80359623
google	rs80359623
pharmgkb	rs80359623
gwascentral	rs80359623
openSNP	rs80359623
23andMe	rs80359623
SNPshot	rs80359623
SNPdbe	rs80359623
MSV3d	rs80359623
GWAS Ctlg	rs80359623

Max Magnitude

6

rs80359623, also known as 6985delCT, c.6757_6758delCT and p.Leu2253Phefs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359623(-;-)
Alt	rs80359623(-;-)
Reference	Rs80359623(TC;TC)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32915249_32915250delCT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000045041.3, RCV000113638.3, RCV000162933.2,