rs80359605

plus

Geno	Mag	Summary
(-;TG)	6	BRCA2 variant considered pathogenic for breast cancer
(TG;TG)	0	common in clinvar

Make rs80359605(-;-)

Reference

GRCh38 38.1/142

Chromosome

13

Position

32340946

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359605
dbSNP (classic)	rs80359605
ClinGen	rs80359605
ebi	rs80359605
HLI	rs80359605
Exac	rs80359605
Gnomad	rs80359605
Varsome	rs80359605
LitVar	rs80359605
Map	rs80359605
PheGenI	rs80359605
Biobank	rs80359605
1000 genomes	rs80359605
hgdp	rs80359605
ensembl	rs80359605
geneview	rs80359605
scholar	rs80359605
google	rs80359605
pharmgkb	rs80359605
gwascentral	rs80359605
openSNP	rs80359605
23andMe	rs80359605
SNPshot	rs80359605
SNPdbe	rs80359605
MSV3d	rs80359605
GWAS Ctlg	rs80359605

Max Magnitude

6

rs80359605, also known as 6819delTG, c.6591_6592delTG and p.Thr2197_Glu2198ThrAsnfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359605(-;-)
Alt	rs80359605(-;-)
Reference	Rs80359605(TG;TG)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32915083_32915084delTG
CLNSRC	Breast Cancer Information Core (BRCA2) OMIM Allelic Variant
CLNACC	RCV000009904.12, RCV000044989.6, RCV000131037.3, RCV000215210.1,