rs80359587

plus

Geno	Mag	Summary
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs80359587(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32340786

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359587
dbSNP (classic)	rs80359587
ClinGen	rs80359587
ebi	rs80359587
HLI	rs80359587
Exac	rs80359587
Gnomad	rs80359587
Varsome	rs80359587
LitVar	rs80359587
Map	rs80359587
PheGenI	rs80359587
Biobank	rs80359587
1000 genomes	rs80359587
hgdp	rs80359587
ensembl	rs80359587
geneview	rs80359587
scholar	rs80359587
google	rs80359587
pharmgkb	rs80359587
gwascentral	rs80359587
openSNP	rs80359587
23andMe	rs80359587
SNPshot	rs80359587
SNPdbe	rs80359587
MSV3d	rs80359587
GWAS Ctlg	rs80359587

Merged from

Rs886038147

Max Magnitude

6

rs80359587, also known as c.6434delA, 6659delA, c.6431_6431delA and p.Glu2144=fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359587(-;-)
Alt	rs80359587(-;-)
Reference	Rs80359587(A;A)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2
Reversed	0
HGVS	NC_000013.10:g.32914926delA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044944.2, RCV000241168.3,