rs80359491

plus

Geno	Mag	Summary
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs80359491(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32339535

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359491
dbSNP (classic)	rs80359491
ClinGen	rs80359491
ebi	rs80359491
HLI	rs80359491
Exac	rs80359491
Gnomad	rs80359491
Varsome	rs80359491
LitVar	rs80359491
Map	rs80359491
PheGenI	rs80359491
Biobank	rs80359491
1000 genomes	rs80359491
hgdp	rs80359491
ensembl	rs80359491
geneview	rs80359491
scholar	rs80359491
google	rs80359491
pharmgkb	rs80359491
gwascentral	rs80359491
openSNP	rs80359491
23andMe	rs80359491
SNPshot	rs80359491
SNPdbe	rs80359491
MSV3d	rs80359491
GWAS Ctlg	rs80359491

Max Magnitude

6

rs80359491, also known as 5408delA, c.5180_5180delA and p.Asn1727Metfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359491(-;-)
Alt	rs80359491(-;-)
Reference	Rs80359491(A;A)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2
Reversed	0
HGVS	NC_000013.10:g.32913672delA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044594.2, RCV000113394.3,