rs80359264

plus

Geno	Mag	Summary
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs80359264(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32332616

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359264
dbSNP (classic)	rs80359264
ClinGen	rs80359264
ebi	rs80359264
HLI	rs80359264
Exac	rs80359264
Gnomad	rs80359264
Varsome	rs80359264
LitVar	rs80359264
Map	rs80359264
PheGenI	rs80359264
Biobank	rs80359264
1000 genomes	rs80359264
hgdp	rs80359264
ensembl	rs80359264
geneview	rs80359264
scholar	rs80359264
google	rs80359264
pharmgkb	rs80359264
gwascentral	rs80359264
openSNP	rs80359264
23andMe	rs80359264
SNPshot	rs80359264
SNPdbe	rs80359264
MSV3d	rs80359264
GWAS Ctlg	rs80359264

Merged from

Rs864622302

Max Magnitude

6

rs80359264, also known as 1366delA, c.1138_1138delA and p.Ser380Valfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

23andMe name: i709063

ClinVar
Risk	rs80359264(-;-)
Alt	rs80359264(-;-)
Reference	Rs80359264(A;A)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32906753delA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000043744.5, RCV000077251.5, RCV000132193.2,