rs6489188
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs6489188(C;C) |
| Make rs6489188(C;T) |
| Make rs6489188(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 122176229 |
| Gene | LRRC43 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6489188 |
| dbSNP (classic) | rs6489188 |
| ClinGen | rs6489188 |
| ebi | rs6489188 |
| HLI | rs6489188 |
| Exac | rs6489188 |
| Gnomad | rs6489188 |
| Varsome | rs6489188 |
| LitVar | rs6489188 |
| Map | rs6489188 |
| PheGenI | rs6489188 |
| Biobank | rs6489188 |
| 1000 genomes | rs6489188 |
| hgdp | rs6489188 |
| ensembl | rs6489188 |
| geneview | rs6489188 |
| scholar | rs6489188 |
| rs6489188 | |
| pharmgkb | rs6489188 |
| gwascentral | rs6489188 |
| openSNP | rs6489188 |
| 23andMe | rs6489188 |
| SNPshot | rs6489188 |
| SNPdbe | rs6489188 |
| MSV3d | rs6489188 |
| GWAS Ctlg | rs6489188 |
| GMAF | 0.2332 |
| Max Magnitude | 0 |
SNPs in the IL31 gene have been associated with nonatopic eczema. Three haplotypes comprised 94% of the haplotypes identified in a German group of patients, defined as follows:
Haplotype A: rs6489188(G) and rs11608363(A)
Haplotype B: rs6489188(A) and rs11608363(G)
Haplotype C: rs6489188(G) and rs11608363(G)
Individuals homozygous for haplotype A were strongly associated with nonatopic eczema compared to individuals not carrying that haplotype. [PMID 17900679]
