rs3825776
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 1 | Normal risk for ALS |
| (A;G) | 1.5 | 1.3x increased risk for ALS |
| (G;G) | 2 | >1.3x increased risk for ALS |
| (T;T) | 0 |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 58454631 |
| Gene | LIPC, LIPC-AS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3825776 |
| dbSNP (classic) | rs3825776 |
| ClinGen | rs3825776 |
| ebi | rs3825776 |
| HLI | rs3825776 |
| Exac | rs3825776 |
| Gnomad | rs3825776 |
| Varsome | rs3825776 |
| LitVar | rs3825776 |
| Map | rs3825776 |
| PheGenI | rs3825776 |
| Biobank | rs3825776 |
| 1000 genomes | rs3825776 |
| hgdp | rs3825776 |
| ensembl | rs3825776 |
| geneview | rs3825776 |
| scholar | rs3825776 |
| rs3825776 | |
| pharmgkb | rs3825776 |
| gwascentral | rs3825776 |
| openSNP | rs3825776 |
| 23andMe | rs3825776 |
| SNPshot | rs3825776 |
| SNPdbe | rs3825776 |
| MSV3d | rs3825776 |
| GWAS Ctlg | rs3825776 |
| GMAF | 0.4169 |
| Max Magnitude | 2 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs3825776, a SNP in the region of the LIPC gene on chromosome 15, has been associated with the sporadic form of ALS (Lou Gehrig's disease) in a study of 1000+ European patients. The odds ratio for the risk allele rs3825776(G) is 1.34 (CI: 1.12 - 1.46). [PMID 18084291]
[PMID 18078817
] Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics.
