rs273899703

minus

Geno	Mag	Summary
(-;A)	6	BRCA1 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs273899703(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43092305

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs273899703
dbSNP (classic)	rs273899703
ClinGen	rs273899703
ebi	rs273899703
HLI	rs273899703
Exac	rs273899703
Gnomad	rs273899703
Varsome	rs273899703
LitVar	rs273899703
Map	rs273899703
PheGenI	rs273899703
Biobank	rs273899703
1000 genomes	rs273899703
hgdp	rs273899703
ensembl	rs273899703
geneview	rs273899703
scholar	rs273899703
google	rs273899703
pharmgkb	rs273899703
gwascentral	rs273899703
openSNP	rs273899703
23andMe	rs273899703
SNPshot	rs273899703
SNPdbe	rs273899703
MSV3d	rs273899703
GWAS Ctlg	rs273899703

Max Magnitude

6

rs273899703, also known as 3345delA, c.3226_3226delA and p.Arg1076Glufs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs273899703(-;-)
Alt	rs273899703(-;-)
Reference	Rs273899703(A;A)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41244322delT
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000048104.2, RCV000112032.3,