rs2266886
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | normal | |
| (C;T) | 0.26x reduced risk for Meniere's disease | |
| (T;T) | 0.26x reduced risk for Meniere's disease |
| Reference | GRCh38 38.1/141 |
| Chromosome | X |
| Position | 153965901 |
| Gene | HCFC1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2266886 |
| dbSNP (classic) | rs2266886 |
| ClinGen | rs2266886 |
| ebi | rs2266886 |
| HLI | rs2266886 |
| Exac | rs2266886 |
| Gnomad | rs2266886 |
| Varsome | rs2266886 |
| LitVar | rs2266886 |
| Map | rs2266886 |
| PheGenI | rs2266886 |
| Biobank | rs2266886 |
| 1000 genomes | rs2266886 |
| hgdp | rs2266886 |
| ensembl | rs2266886 |
| geneview | rs2266886 |
| scholar | rs2266886 |
| rs2266886 | |
| pharmgkb | rs2266886 |
| gwascentral | rs2266886 |
| openSNP | rs2266886 |
| 23andMe | rs2266886 |
| SNPshot | rs2266886 |
| SNPdbe | rs2266886 |
| MSV3d | rs2266886 |
| GWAS Ctlg | rs2266886 |
| GMAF | 0.4988 |
| Max Magnitude | 0 |
rs2266886 is a SNP in the host cell factor C1 HCFC1 gene, encoding a protein also known as the VP16-accessory protein.
A case-control association study concluded that carriers of a rs2266886(T) minor allele at this SNP have a reduced risk for developing Meniere's disease, by an odds ratio of 0.26 (CI: 0.010-0.65; p = 0.003)[PMID 18520591
]
