[PMID 20587604
] Fine Mapping of Chromosome 15q25.1 Lung Cancer Susceptibility in African Americans
[PMID 18519524] Variants in nicotinic receptors and risk for nicotine dependence.
[PMID 18618000] A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.
[PMID 18759969] In search of causal variants: refining disease association signals using cross-population contrasts.
[PMID 19029397] Nicotinic receptor gene variants influence susceptibility to heavy smoking.
[PMID 19443489] Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
[PMID 19706762] The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
[PMID 23397474] Polymorphisms of CHRNA5-CHRNA3-CHRNB4 Gene Cluster and NSCLC Risk in Chinese Population
| GWAS snp
|
| PMID
|
[PMID 22837378]
|
| Trait
|
Airflow obstruction
|
| Title
|
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.
|
| Risk Allele
|
|
| P-val
|
2E-7
|
| Odds Ratio
|
1.18
|
] Fine Mapping of Chromosome 15q25.1 Lung Cancer Susceptibility in African Americans
