rs140926439
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs140926439(C;C) |
| Make rs140926439(C;T) |
| Make rs140926439(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 2 |
| Position | 215424292 |
| Gene | FN1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs140926439 |
| dbSNP (classic) | rs140926439 |
| ClinGen | rs140926439 |
| ebi | rs140926439 |
| HLI | rs140926439 |
| Exac | rs140926439 |
| Gnomad | rs140926439 |
| Varsome | rs140926439 |
| LitVar | rs140926439 |
| Map | rs140926439 |
| PheGenI | rs140926439 |
| Biobank | rs140926439 |
| 1000 genomes | rs140926439 |
| hgdp | rs140926439 |
| ensembl | rs140926439 |
| geneview | rs140926439 |
| scholar | rs140926439 |
| rs140926439 | |
| pharmgkb | rs140926439 |
| gwascentral | rs140926439 |
| openSNP | rs140926439 |
| 23andMe | rs140926439 |
| SNPshot | rs140926439 |
| SNPdbe | rs140926439 |
| MSV3d | rs140926439 |
| GWAS Ctlg | rs140926439 |
| Max Magnitude | 0 |
aka NM_212482.4(FN1):c.1070G>A (p.Gly357Glu)
[PMID 38598053] Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease
From Abstract (2024): "A independent analysis in a large cohort of 7185 APOEε4 homozygous carriers found that rs140926439 variant in FN1 was protective of AD (OR = 0.29; 95% CI [0.11, 0.78], P = 0.014) and delayed age at onset of disease by 3.37 years (95% CI [0.42, 6.32], P = 0.025)."[PMID 38598053]
