rs12597511
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | normal | |
| (C;T) | slightly higher blood pressure | |
| (T;T) | slightly higher blood pressure |
| Reference | GRCh38 38.1/141 |
| Chromosome | 16 |
| Position | 31133898 |
| Gene | PRSS8 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs12597511 |
| dbSNP (classic) | rs12597511 |
| ClinGen | rs12597511 |
| ebi | rs12597511 |
| HLI | rs12597511 |
| Exac | rs12597511 |
| Gnomad | rs12597511 |
| Varsome | rs12597511 |
| LitVar | rs12597511 |
| Map | rs12597511 |
| PheGenI | rs12597511 |
| Biobank | rs12597511 |
| 1000 genomes | rs12597511 |
| hgdp | rs12597511 |
| ensembl | rs12597511 |
| geneview | rs12597511 |
| scholar | rs12597511 |
| rs12597511 | |
| pharmgkb | rs12597511 |
| gwascentral | rs12597511 |
| openSNP | rs12597511 |
| 23andMe | rs12597511 |
| SNPshot | rs12597511 |
| SNPdbe | rs12597511 |
| MSV3d | rs12597511 |
| GWAS Ctlg | rs12597511 |
| GMAF | 0.4692 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs12597511, a SNP in the serine protease prostasin PRSS8 gene, has been linked to higher blood pressure (and thus risk of hypertension) in a study of healthy subjects.
Both African-Americans and European-Americans with rs12597511(C;T) or rs12597511(T;T) genotypes had (slightly) higher systolic and diastolic blood pressure than (C;C) individuals.[PMID 18583984
]
[PMID 33130844] Association between preeclampsia and prostasin polymorphism in Pakistani females.
