rs1258763
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Make rs1258763(A;A) |
| Make rs1258763(A;G) |
| Make rs1258763(G;G) |
| Reference | GRCh38 38.1/142 |
| Chromosome | 15 |
| Position | 32758222 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1258763 |
| dbSNP (classic) | rs1258763 |
| ClinGen | rs1258763 |
| ebi | rs1258763 |
| HLI | rs1258763 |
| Exac | rs1258763 |
| Gnomad | rs1258763 |
| Varsome | rs1258763 |
| LitVar | rs1258763 |
| Map | rs1258763 |
| PheGenI | rs1258763 |
| Biobank | rs1258763 |
| 1000 genomes | rs1258763 |
| hgdp | rs1258763 |
| ensembl | rs1258763 |
| geneview | rs1258763 |
| scholar | rs1258763 |
| rs1258763 | |
| pharmgkb | rs1258763 |
| gwascentral | rs1258763 |
| openSNP | rs1258763 |
| 23andMe | rs1258763 |
| SNPshot | rs1258763 |
| SNPdbe | rs1258763 |
| MSV3d | rs1258763 |
| GWAS Ctlg | rs1258763 |
| GMAF | 0.4605 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 20023658] |
| Trait | Nonsyndromic cleft lip with or without cleft palate |
| Title | Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate |
| Risk Allele | A |
| P-val | 0.000001 |
| Odds Ratio | 1.52 [1.23-1.86] |
blog The two most significant associations found were between nose width and SNP rs1258763 near the GREM1 gene in the German cohort (P=6 × 10?4), and between bizygomatic distance and SNP rs987525 at 8q24.21 near the CCDC26 gene (P=0.017)
[PMID 21694738
] Genetic determination of human facial morphology: links between cleft-lips and normal variation.
Associated with European Facial Appearance 10.1371/journal.pgen.1002932
| GWAS snp | |
|---|---|
| PMID | [PMID 22863734]
|
| Trait | Orofacial clefts |
| Title | Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. |
| Risk Allele | |
| P-val | 2E-6 |
| Odds Ratio | NR NR |
[PMID 26043427] Association between polymorphisms at the GREM1 locus and the risk of nonsyndromic cleft lip with or without cleft palate in the Polish population
[PMID 30402937] Understanding the participation of GREM1 polymorphisms in nonsyndromic cleft lip with or without cleft palate in the Brazilian population.
