rs11190870

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(C;T)	2	Possibly increased risk of scoliosis
(T;T)	2.5	Possibly even more increased risk of scoliosis

Make rs11190870(C;C)

Reference

GRCh38 38.1/142

Chromosome

10

Position

101219450

is a	snp
is	mentioned by
dbSNP	rs11190870
dbSNP (classic)	rs11190870
ClinGen	rs11190870
ebi	rs11190870
HLI	rs11190870
Exac	rs11190870
Gnomad	rs11190870
Varsome	rs11190870
LitVar	rs11190870
Map	rs11190870
PheGenI	rs11190870
Biobank	rs11190870
1000 genomes	rs11190870
hgdp	rs11190870
ensembl	rs11190870
geneview	rs11190870
scholar	rs11190870
google	rs11190870
pharmgkb	rs11190870
gwascentral	rs11190870
openSNP	rs11190870
23andMe	rs11190870
SNPshot	rs11190870
SNPdbe	rs11190870
MSV3d	rs11190870
GWAS Ctlg	rs11190870

GMAF

0.4238

Max Magnitude

2.5

?	(C;C) (C;T) (T;T)	28

[PMID 21331621] Genetic variants in ultraconserved elements and risk of breast cancer in Chinese population

The T allele of this SNP is associated with an increased risk of scoliosis in adolescent Japanese girls. [1]

GWAS snp
PMID	[PMID 22019779]
Trait
Title	A genome-wide association study identifies common variants near LBX1 associated with adolescent idiopathic scoliosis.
Risk Allele
P-val	1E-19
Odds Ratio	1.5600 None

[PMID 23096252] Association of rs11190870 near LBX1 with adolescent idiopathic scoliosis susceptibility in a Han Chinese population.

[PMID 24878781] Association of rs11190870 near LBX1 with adolescent idiopathic scoliosis in East Asians: a systematic review and meta-analysis

[PMID 28187071] Genetic Polymorphism of LBX1 is Associated with Adolescent Idiopathic Scoliosis in Northern Chinese Han Population.

[PMID 29535018] The association of rs11190870 near LBX1 with the susceptibility and severity of AIS, a meta-analysis.