| GWAS snp
|
| PMID
|
[PMID 20395239 ]
|
| Trait
|
Optic disc size (rim)
|
| Title
|
Genome-wide association identifies ATOH7 as a major gene determining human optic disc size
|
| Risk Allele
|
C
|
| P-val
|
0.000009
|
| Odds Ratio
|
0.15 [0.06-0.24] unit increase
|
[PMID 21398277] Genetic variants associated with optic nerve vertical cup-to-disc ratio are risk factors for primary open angle glaucoma in a US Caucasian population
[PMID 22584021] Association between Genetic Variants Associated with Vertical Cup-to-Disc Ratio and Phenotypic Features of Primary Open-Angle Glaucoma
| GWAS snp
|
| PMID
|
[PMID 22570617]
|
| Trait
|
|
| Title
|
Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.
|
| Risk Allele
|
A
|
| P-val
|
4E-11
|
| Odds Ratio
|
1.3200 None
|
| GWAS snp
|
| PMID
|
[PMID 22419738]
|
| Trait
|
|
| Title
|
A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
|
| Risk Allele
|
T
|
| P-val
|
9E-8
|
| Odds Ratio
|
1.2700 None
|
[PMID 22840486] Genetic investigation into the endophenotypic status of central corneal thickness and optic disc parameters in relation to open-angle glaucoma.
[PMID 25849520] Quantitative Trait Locus Analysis of SIX1-SIX6 With Retinal Nerve Fiber Layer Thickness in Individuals of European Descent
[PMID 25711633] Genetic Variants Associated With Different Risks for High Tension Glaucoma and Normal Tension Glaucoma in a Chinese Population
[PMID 28717659] Identification and characterization of variants and a novel 4 bp deletion in the regulatory region of SIX6, a risk factor for primary open-angle glaucoma.
[PMID 32933932] Genetic analysis of primary open-angle glaucoma-related risk alleles in a Korean population: the GLAU-GENDISK study.
]
