NUDT15
From SNPedia
| is a | gene |
| is | mentioned by |
| ClinVar | NUDT15 |
| GeneCards | NUDT15 |
| Diseases | NUDT15 |
| wikipedia | NUDT15 |
| NUDT15 | |
| gopubmed | NUDT15 |
| EVS | NUDT15 |
| HEFalMp | NUDT15 |
| MyGene2 | NUDT15 |
| 23andMe | NUDT15 |
| # SNPs | 4 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs116855232 | 4 | 48,045,719 | |
| rs147390019 | 0 | 48,045,720 | |
| rs186364861 | 0 | 48,037,798 | |
| rs869320766 | 0 | 48,037,801 |
Located on chromosome 13, the NUDT15 gene encodes the nudix hydrolase 15 enzyme. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia.GHR
Note that multiple pseudogenes of this gene have been identified, and technologies (such as DNA chips used by many direct-to-consumer companies) may not be accurate for this reason.
